The domaine dates back to the building of the house and cellar at Clos de la Barre by the Boch family in 1869. However, the real creator of the estate was Comte Jules Lafon who married Mlle Marie Boch on St Vincent's day 1894. He was shrewd enough to buy exceptionally well-sited plots in the best vineyards of Meursault and Volnay, as well as a treasured piece of Le Montrachet, acquired in 1919, thought he first vintage bottled at the domaine was not until 1935.

Domaine des Comtes Lafon is not only a leading producer in Meursault village but also one of the few in the Cote d'Or that produces equally good Chardonnay and Pinot Noir. Under the care of Dominique Lafon, the domaine is cultivated according to biodynamic principles with no use of herbicides or chemical spray. This is why its range of white Burgundy has become the very pinnacle of the region, characterized with superlative fruit, power, complexity and total harmony. Dominique Lafon has been in charge since 1985, taking over a domaine which already had a reputation for outstanding, if irregular, whites and potentially good reds. He officially retired in December 2021, handing over to his daughter Léa and his nephew Pierre, so the family future at the domaine is assured.

Not only are the Lafons' holdings in the best vineyards of Meursault and Volnay, but they are mostly very well placed within the vineyards. While remaining faithful to its Meursault roots, Domaine des Comtes Lafon has grown through the acquisition (shared with Domaine Roulot) of the former Domaine René Manuel, bringing two new premiers crus, Poruzots and Bouchères, from 2011, and completing the set of all six premiers crus in the central grouping, from Perrières and Charmes through to Les Gouttes d'Or.

Les Heritiers du Comte Lafon was established in 1999, achieving new standards in Macon. This domaine covers 14 hectares where biodynamic techniques, low yield and hand-harvest are in practice.